John F. Kelly, the White House chief of staff, is likely to leave his post in the next few days, ending a tumultuous 16-month tenure still among the longest for a senior aide to President Trump, two people with direct knowledge of the developments said Friday.
Mr. Kelly and Mr. Trump have grown weary with each other. But Mr. Trump, according to several senior administration officials and people close to him, has so far been unable to bring himself to personally fire a retired four-star military general.
Still, both are said to be ready for Mr. Kelly to move on.
It is unclear who the replacement would be. Nick Ayers, the vice president’s chief of staff, is seen as a leading candidate. He is supported by Jared Kushner and Ivanka Trump, the president’s son-in-law and daughter, who both serve as senior West Wing advisers and who, according to several officials, are trying to expand their influence internally and in the re-election campaign.
The White House senior staff meeting on Friday morning was canceled, according to three officials. But there is a holiday senior staff dinner scheduled for Friday night, and people said they expected Mr. Kelly to be there.